We would like to tell you about an exciting new opportunity for patients with sinusitis that is about to start. Perhaps you’ll be interested in participating! It is being conducted by an independent group of clinicians who are not influenced or affiliated with Lanto Health.

This team of researchers and clinicians recently completed a sinusitis study in a group of difficult to treat chronic sinusitis patients, who had all undergone multiple sinus surgeries. In the study they had been using Lanto Sinus with these patients, with very good results. 

Based on the positive outcomes in this group of individuals with chronic sinusitis, the clinicians decided to expand their clinical observations.

The researchers chose Lanto Sinus because of the specific strain of L. sakei in it (L. sakei Probio65). This strain is known to be especially effective against a variety of species of harmful bacteria that commonly cause problems in sinusitis. L. sakei also raises IL-12 levels, a substance involved in our immune system functioning. The researchers thought that microbial imbalances in chronic sinusitis could contribute to IL-12 signaling defects, resulting in low IL-12 levels.

HOW TO PARTICIPATE

To find out more regarding this clinical opportunity as well as potentially participating as a research subject, please click on this link. Going to this site (which is HIPPA compliant), filling out the information, and indicating you want to participate will alert the clinical team in your interest. They will then connect you with one of Amerimmune’s providers in your state. 

Participants will teleconference with the medical provider, and then will be directed to go to a lab to have blood drawn for a pSTAT4 phosphorylation assay, which will measure immune health related to IL-12. Results will go to the ordering doctor, who will then share the results with the participant.

The clinicians involved are Dr. Michael Abidin, an ENT doctor in Alexandria, Virginia, and Dr. Oral Alpan, an Allergist Immunologist in Mc Lean, VA.  Their initial study is currently in pre-print, which means it is undergoing peer-review before publication. Their goal is to understand what is going on in chronic sinusitis, especially from an immunological angle.

THE RESEARCHERS SUMMARIZE THEIR INITIAL STUDY:

Objective: We wanted to find out more about chronic rhinosinusitis (CRS), a sinus problem that affects 5% to 15% of people all over the world and costs a lot in healthcare. We need to find better ways to predict and treat CRS.

Study Design: We looked at a group of CRS patients who required surgery, and who had already undergone multiple sinus procedures, and compared them to healthy people without a history of sinusitis, by using their blood samples. This was done in clinics where patients visit, but don't stay overnight.

To find out more regarding this clinical opportunity as well as potentially participating as a research subject, please click on this link.